Alkyl chlorides
Sigma Aldrich Fine Chemicals Biosciences 1 Methylnaphthalene 955KG
1-Methylnaphthalene occurs in Chinese raw spirits brown millet milled millet and millet bran. This volatile organic compound (VOC) is also found in the diesel engine exhaust gas and in the manures of cow hog and chicken.
![Medchemexpress LLC 1H-pyrazolo[3,4-d]pyrimidin-4-amine, N,1-diphenyl- | 68380-53-0 | 99.5% | 287.32 Da | C17H13N5 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289259.png-250.jpg)
Medchemexpress LLC 1H-pyrazolo[3,4-d]pyrimidin-4-amine, N,1-diphenyl- | 68380-53-0 | 99.5% | 287.32 Da | C17H13N5 | 10 MG
Antifungal agent 112 (Compound 1e) is a purified small-molecule research compound that shows potent in vitro antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus fumigatus (reported MICs 0.0024, 0.0022, and 0.0028 M, respectively). It is supplied as a high-purity powder, soluble in DMSO, and intended for laboratory research use.
- High purity suitable for research use.
- Potent in vitro activity against Candida and Aspergillus species.
- Soluble in DMSO at the concentrations described by the supplier.
- Stable as a powder when stored under recommended conditions.
- Available in small milligram pack sizes for laboratory experiments.
Medchemexpress LLC Spi-112 | 1051387-90-6 | MFCD31620831 | 98.0% | 468.46 g/mol | C22H17FN4O5S | 1 ML
SPI-112 is a potent, selective, and competitive inhibitor of SHP2 (PTPN11) used for in vitro biochemical and biophysical studies. It inhibits SHP2 with an IC50 of approximately 1 μM, with weaker activity against related phosphatases. Kinetic and binding data indicate competitive inhibition (Ki ≈ 0.8 μM) and 1:1 binding by SPR (KD ≈ 1.3 μM). The compound is not cell permeable and is supplied for research applications.
- Inhibits SHP2 with IC50 ≈ 1 μM.
- Shows selectivity over related phosphatases (IC50s 18.3 μM for PTP, 14.5 μM for PTP1B).
- Exhibits competitive inhibition kinetics (Ki ≈ 0.8 μM).
- Binds 1:1 in SPR with KD ≈ 1.3 μM.
- Not cell permeable due to polar or charged functional groups.
- Supplied as a solid and as a 10 mM solution for in vitro assays.
- High purity suitable for biochemical assays (≈98%).
- Store solid at 4°C; in solvent store at -80°C (long term) or -20°C (short term).
![Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000095535.png-250.jpg)
Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 5mg
Hemagglutinin precursor 114-122 amide is a synthetic peptide fragment derived from the hemagglutinin glycoprotein of Influenza A virus It is designed to present antigenic determinants that facilitate the analysis of peptide-MHC interactions and characterization of influenza-specific immune responses Hemagglutinin precursor 114-122 amide exerts its biological activity primarily by eliciting immune responses against Influenza A virus supporting studies on cytotoxic T-cell reactivity and antigenicity Based on these properties hemagglutinin precursor 114-122 amide holds research potential in immunological assays vaccine antigenicity studies and investigations of antiviral immune responses
![Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264388.png-250.jpg)
Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG
UC-112 is a small-molecule inhibitor of inhibitor of apoptosis proteins (IAP) developed for cellular studies of apoptosis and anticancer activity. It produces cytotoxic and antiproliferative effects across multiple human cancer cell lines and is supplied as a solid or as a DMSO solution for research applications.
- Potent IAP inhibitor with reported cell-assay IC50 = 0.7-3.4 μM.
- Demonstrated activity in PC-3, A-375, M14, and DU-145 cell lines.
- High purity (98.92%) suitable for in vitro studies.
- Molecular formula C22H24N2O2; molecular weight 348.44.
- Available as milligram quantities and as a 10 mM solution in DMSO.
- Intended for research use in apoptosis and anticancer mechanism studies.
Medchemexpress LLC Antifungal agent 112 | 68380-53-0 | 99.5% | 287.32 | 25 MG
Antifungal agent 112 (Compound 1e) exhibits antifungal activity against *Candida albicans*, *Aspergillus niger*, and *Aspergillus fumigatus* with MIC values of 0.0024, 0.0022, and 0.0028 M, respectively. It is for research use only and not sold to patients.
- Antifungal activity against *Candida albicans*, *Aspergillus niger*, and *Aspergillus fumigatus*.
- Available in various quantities (5 mg, 10 mg, 25 mg, 50 mg).
- Controlled substance, not for sale in all territories.
Medchemexpress LLC UC-112 | 383392-66-3 | 98.9% | 100 MG
UC-112 is a survivin and XIAP modulator exhibiting anticancer activity. It functions by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal pathway. This compound also effectively reduces XIAP levels in in vivo tumor models, leading to the activation of caspase-3/7 and caspase-9, and ultimately inducing apoptosis in cancer cells. It is suitable for research on melanoma, prostate cancer, and other cancer-related studies.
- Selectively downregulates and degrades survivin
- Reduces XIAP levels in in vivo tumor models
- Activates caspase-3/7 and caspase-9
- Induces cancer cell apoptosis
- Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
- Alters cell cycle distribution in A375 melanoma cells
- Inhibits human melanoma tumor growth in nude mice